Guest:

Dr. Bernardo Franklin is a Professor at the University of Bonn. His lab studies the role of innate immunity in sterile inflammation and in infectious diseases. More recently, their research has focused on blood platelets and their effects on innate immunity, systemic inflammation and cancer.

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The Immunology Science Round Up

T Cell Mediated Cross-Reactivity between Seasonal Coronaviruses and SARS-CoV-2 – Researchers found that CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses.

COVID-19 Recovered Individuals May Only Require a Single mRNA Vaccine Dose – In individuals who have already recovered from COVID-19, a single mRNA vaccine dose was sufficient to achieve peak antibody and memory B cell responses.

Forcing Cancer Out of “Stealth Mode” – DNA methyl transferase inhibitors alter the surface proteome and mediate cytoskeletal reorganization, priming γδ T cells to kill lung cancer cells.

Maternal Treg Cells Can Reverse Behavioral Abnormalities in Adult Mouse Offspring  – Behavioral abnormalities caused by maternal immune activation could be rescued by transferring pathogen-activated maternal Treg cells.

Photo Reference: Courtesy of Dr. Bernardo Franklin