Ep. 13: “Pathogens, Autoantigens, and Antigens” Featuring Dr. Frances Lund
Dr. Frances Lund is the Charles H. McCauley Professor and Chair of the Department of Microbiology at the University of Alabama at Birmingham. Her lab showed that B cells not only make antibodies, but also produce cytokines that modulate the microenvironment. She currently studies the many roles of B cells, how to target B cells gone bad, and nasal vaccines for respiratory illnesses.
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The Immunology Science Round Up
A COVID-19 Vaccine Targeting CD40 – Researchers fused a CD40 monoclonal antibody to a SARS-CoV-2 protein, which stimulated dendritic cells and boosted the immune response of monkeys already exposed to the virus.
A T Cell Cancer Vaccine – Scientists generated a therapeutic cancer vaccine by genetically modifying T cells to deliver antigens and adjuvant signals to lymphoid tissues.
Dendritic Cells in Intestinal Immunity – Intestinal dendritic cells have local specializations that depend on the microenvironment.
Stress and the Immune System – Psychological stress primes monocytes to an inflammatory state.
Image courtesy of Dr. Frances Lund