Guest:

Dr. James Crowe is the Director of the Vanderbilt Vaccine Center. Their group uses a very broad array of techniques including molecular and cellular biology, state-of-the-art imaging and flow cytometry, bioinformatics, and bioengineering approaches to attack the scientific problems that are of interest to them: major human pathogens.

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The Immunology Science Round Up

COVID-19 Vaccine Effectiveness against the Delta Variant – The Pfizer and Astrazeneca vaccines are highly protective against the delta variant of COVID-19 after two doses.

Immune Cell Mechanisms in Colitis – Researchers identified an inverse correlation between inflammatory bowel disease severity and Cox2 expression, uncovering an active immune pathway that may be targeted to reduce inflammation.

T Cell Specificity in Melanoma – Scientists took an in-depth look at the relationship between T cell receptors and T cell phenotypes in patient-derived melanoma cell lines.

Overcoming PD-1 Blockade Resistance in Lung Cancer – Researchers studied the transcriptional programs of neoantigen-specific tumor-infiltrating lymphocytes in PD-1 treated lung cancers.

Photo Reference: Courtesy of Dr. James Crowe