Dr. Leonardo Ferreira is an Assistant Professor of Microbiology and Immunology at the Medical University of South Carolina. The Ferreira lab uses CARs and other engineered immune receptors to dissect how specificity, affinity, and signaling modulate the function of different T cells subsets in tolerance and immunity. He talks about how CAR Tregs could prevent transplant rejection and treat Type 1 diabetes. He also discusses mixing and matching immune cells, the freedom to pursue multiple ideas in academia, and science outreach in Bolivia
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Dr. Karen Edelblum is an Assistant Professor of Pathology and Laboratory Medicine at Rutgers New Jersey Medical School. She discusses γδ T cells and immune-epithelial cross-talk in inflammatory bowel disease. She also talks about intravital microscopy and decorating immunology-themed cakes!
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Dr. Mark Kaplan is the Chair of the Department of Microbiology and Immunology at Indiana University School of Medicine. He is currently the Editor-In-Chief for the American Association of Immunologists’ journal ImmunoHorizons. Much of Dr. Kaplan’s work has focused on understanding the function of transcription factors in the development of T helper cell subsets. He talks about the role of T helper 9 cells in lung inflammation and γδ T cells in wound healing. He also discusses ImmunoHorizons and how it provides a home for solid immunological research that may otherwise remain unpublished.
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Dr. Laura Mackay is a Professor and Laboratory Head at the Peter Doherty Institute for Infection and Immunity at the University of Melbourne. She talks about her tissue-resident memory T cell research and her ongoing collaboration with Pfizer to identify and validate new targets for cancer therapy.
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Dr. Mark Shlomchik is a UPMC Endowed Distinguished Professor and Chair of the Department of Immunology at the University of Pittsburgh. He is also a Founder and Chief Scientific Officer of BlueSphere Bio, a company working to create individualized T cell therapies for the treatment of cancer. Dr. Shlomchik’s lab focuses on systemic autoimmune diseases, long-lived B cell immunity, and immunopathogenesis. He talks about the role of toll-like receptors in lupus, how his autoimmune disease research led to potential cancer therapies, and starting a biotech company with his brother.
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